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1

CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3

Edze R. Westra, Paul B.G. van Erp, Tim Künne, Shi Pey Wong, Raymond H.J. Staals, Christel L.C. Seegers, Sander Bollen, Matthijs M. Jore, Ekaterina Semenova, Konstantin Severinov, Willem M. de Vos, Rem

Journal:

Year:

2012

Language:

english

File:

PDF, 1.55 MB

english, 2012

2

Planting the seed: target recognition of short guide RNAs

Künne, Tim, Swarts, Daan C., Brouns, Stan J.J.

Journal:

Trends in Microbiology

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

3

Wissensaustausch in Sachen Reinigungstechnik

Prof. Dr.-Ing. Bernd Künne,Dipl.-Ing. Tim Richard

Journal:

JOT Journal für Oberflächentechnik

Year:

2007

File:

PDF, 106 KB

2007

4

Projekt „Erzeugnissauberkeit in der Automobilzulieferindustrie“ gestartet

Prof. Dr.-Ing. Bernd Künne,Dipl.-Ing. Tim Richard

Journal:

JOT Journal für Oberflächentechnik

Year:

2006

Language:

german

File:

PDF, 541 KB

german, 2006

5

Two Distinct DNA Binding Modes Guide Dual Roles of a CRISPR-Cas Protein Complex

Blosser, Timothy R., Loeff, Luuk, Westra, Edze R., Vlot, Marnix, Künne, Tim, Sobota, Małgorzata, Dekker, Cees, Brouns, Stan J.J., Joo, Chirlmin

Journal:

Year:

2015

Language:

english

File:

PDF, 2.57 MB

english, 2015

6

Cas3-Derived Target DNA Degradation Fragments Fuel Primed CRISPR Adaptation

Künne, Tim, Kieper, Sebastian N., Bannenberg, Jasper W., Vogel, Anne I.M., Miellet, Willem R., Klein, Misha, Depken, Martin, Suarez-Diez, Maria, Brouns, Stan J.J.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.06 MB

english, 2016

7

Bacteriophage DNA glucosylation impairs target DNA binding by type I and II but not by type V CRISPR–Cas effector complexes

Vlot, Marnix, Houkes, Joep, Lochs, Silke J.A., Swarts, Daan C., Zheng, Peiyuan, Kunne, Tim, Mohanraju, Prarthana, Anders, Carolin, Jinek, Martin, van der Oost, John, Dickman, Mark J., Brouns, Stan J.J

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 3.25 MB

english, 2017

8

Role of nucleotide identity in effective CRISPR target escape mutations

Künne, Tim, Zhu, Yifan, da Silva, Fausia, Konstantinides, Nico, McKenzie, Rebecca E, Jackson, Ryan N, Brouns, Stan JJ

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 3.50 MB

english, 2018

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